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ENDUR-ACIN® 500mg - Of all the agents to promote healthy cholesterol within normal limits, niacin has the longest clinically documented record, beginning in 1955 and continuing today. Niacin, in the form of nicotinic acid, has an impressive track record of positive effects upon healthy cholesterol levels within normal limits. It is recommended by the National Cholesterol Education Program and the American Heart Association when diet alone is insufficient to maintain cholesterol within normal limits.
Very few niacin products have been subjected to clinical study. Well controlled clinical trials conducted at the University of Minnesota, Harvard University and the Russian Research Center for Preventive Medicine have demonstrated excellent bioavailability and patient tolerance of wax matrix, extended release niacin, (ENDUR-ACIN®) with less than 4% of patients discontinuing due to side effects. Visit our research website to review a complete listing of published literature for wax-matrix niacin.
Traditional or common niacin usage has been limited particularly by so-called "nuisance" side effects including skin flushing associated with tingling and warmth. ENDUR-ACIN®, owing to its unique extended release formulation, eliminates for most individuals the unpleasant skin flushing effect that occurs when taking niacin. ENDUR-ACIN® utilizes a unique wax-matrix process that ensures uniform, continuous release of niacin from the tablet during its 6 - 8 hour transit time through the digestive system. This greatly reduces gastrointestinal upset and gut irritation associated with the buildup of localized concentrations of niacin and skin irritations associated with a rapid rise in blood levels.
ENDUR-ACIN® is usually well tolerated in single doses of 500 - 750 mg. higher single doses can increase the likelihood of flushing, and can therefore be divided into a twice daily regimen to minimize the chance of side effects. Do not use ENDUR-ACIN® if you have a know hypersensitivity to niacin, or active liver disease. Use of any niacin for promoting healthy cholesterol levels within normal limits should always be physician supervised.
Caution: Temporary flushing, itching, or warming of the skin may occur. Do not use without the advice of your physician if you consume more than modest amounts of alcohol, have poorly controlled diabetes, liver disease, gout, active peptic ulcer disease, or unstable angina.
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